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1

Neutralizing Antibody Induction by HIV-1 Envelope Glycoprotein SOSIP Trimers on Iron Oxide Nanoparticles May Be Impaired by Mannose Binding Lectin

Ringe, Rajesh P., Cruz Portillo, Victor M., Dosenovic, Pia, Ketas, Thomas J., Ozorowski, Gabriel, Nogal, Bartek, Perez, Lautaro, LaBranche, Celia C., Lim, Jillian, Francomano, Erik, Wilson, Ian A., Sa

Journal:

Journal of Virology

Year:

2019

File:

PDF, 8.31 MB

2019

2

Stable 293 T and CHO cell lines expressing cleaved, stable HIV-1 envelope glycoprotein trimers for structural and vaccine studies

Chung, Nancy PY, Matthews, Katie, Kim, Helen J, Ketas, Thomas J, Golabek, Michael, de los Reyes, Kevin, Korzun, Jacob, Yasmeen, Anila, Sanders, Rogier W, Klasse, Per, Wilson, Ian A, Ward, Andrew B, Ma

Journal:

Year:

2014

Language:

english

File:

PDF, 1.92 MB

english, 2014

3

Enhancement of α-Helix Mimicry by an α/β-Peptide Foldamer via Incorporation of a Dense Ionic Side-Chain Array

Mortenson, David E., Yun, Hyun Gi, Horne, W. Seth, Ketas, Thomas J., Lu, Min, Moore, John P., Gellman, Samuel H., Johnson, Lisa M.

Journal:

Journal of the American Chemical Society

Year:

2012

Language:

english

File:

PDF, 317 KB

english, 2012

4

Entry inhibitor-based microbicides are active in vitro against HIV-1 isolates from multiple genetic subtypes

Thomas J. Ketas, Susan M. Schader, Juan Zurita, Esther Teo, Victoria Polonis, Min Lu, Per Johan Klasse, John P. Moore

Journal:

Year:

2007

Language:

english

File:

PDF, 490 KB

english, 2007

5

Influences on the design and purification of soluble, recombinant native-like HIV-1 envelope glycoprotein trimers

Ringe, Rajesh P., Yasmeen, Anila, Ozorowski, Gabriel, Go, Eden P., Pritchard, Laura K., Guttman, Miklos, Ketas, Thomas A., Cottrell, Christopher A., Wilson, Ian A., Sanders, Rogier W., Cupo, Albert, C

Journal:

Journal of Virology

Year:

2015

Language:

english

File:

PDF, 1.34 MB

english, 2015

6

Env-glycoprotein heterogeneity as a source of apparent synergy and enhanced cooperativity in inhibition of HIV-1 infection by neutralizing antibodies and entry inhibitors

Thomas J. Ketas, Sophie Holuigue, Katie Matthews, John P. Moore, Per Johan Klasse

Journal:

Year:

2012

Language:

english

File:

PDF, 1.07 MB

english, 2012

7

cGMP production and analysis of BG505 SOSIP.664, an extensively glycosylated, trimeric HIV-1 envelope glycoprotein vaccine candidate

Dey, Antu K., Cupo, Albert, Ozorowski, Gabriel, Sharma, Vaneet K., Behrens, Anna-Janina, Go, Eden P., Ketas, Thomas J., Yasmeen, Anila, Klasse, Per J., Sayeed, Eddy, Desaire, Heather, Crispin, Max, Wi

Journal:

Biotechnology and Bioengineering

Year:

2017

Language:

english

File:

PDF, 896 KB

english, 2017

8

Cell surface expression of CCR5 and other host factors influence the inhibition of HIV-1 infection of human lymphocytes by CCR5 ligands

Thomas J. Ketas, Shawn E. Kuhmann, Ashley Palmer, Juan Zurita, Weijing He, Sunil K. Ahuja, Per Johan Klasse, John P. Moore

Journal:

Year:

2007

Language:

english

File:

PDF, 469 KB

english, 2007

9

Protein Design of a Bacterially Expressed HIV-1 gp41 Fusion Inhibitor †

Deng, Yiqun, Zheng, Qi, Ketas, Thomas J., Moore, John P., Lu, Min

Journal:

Year:

2007

Language:

english

File:

PDF, 344 KB

english, 2007

10

Limited or no protection by weakly or nonneutralizing antibodies against vaginal SHIV challenge of macaques compared with a strongly neutralizing antibody

Dennis R. Burton, Ann J. Hessell, Brandon F. Keele, Per Johan Klasse, Thomas A. Ketas, Brian Moldt, D. Cameron Dunlop, Pascal Poignard, Lara A. Doyle, Lisa Cavacini, Ronald S. Veazey and John P. Moore

Journal:

Proceedings of the National Academy of Sciences

Year:

2011

Language:

english

File:

PDF, 1.09 MB

english, 2011

11

Murine antibody responses to cleaved soluble HIV-1 envelope trimers are highly restricted in specificity

Hu, Joyce K., Crampton, Jordan C., Cupo, Albert, Ketas, Thomas, van Gils, Marit J., Sliepen, Kwinten, de Taeye, Steven W., Sok, Devin, Ozorowski, Gabriel, Deresa, Isaiah, Stanfield, Robyn, Ward, Andre

Journal:

Journal of Virology

Year:

2015

File:

PDF, 2.59 MB

2015

12

Reducing V3 antigenicity and immunogenicity on soluble, native-like HIV-1 Env SOSIP trimers

Ringe, Rajesh P., Ozorowski, Gabriel, Rantalainen, Kimmo, Struwe, Weston B., Matthews, Katie, Torres, Jonathan L., Yasmeen, Anila, Cottrell, Christopher A., Ketas, Thomas J., LaBranche, Celia C., Mont

Journal:

Journal of Virology

Year:

2017

Language:

english

File:

PDF, 3.34 MB

english, 2017

13

Resistance of a human immunodeficiency virus type 1 isolate to a small molecule CCR5 inhibitor can involve sequence changes in both gp120 and gp41

Cleo G. Anastassopoulou, Thomas J. Ketas, Rafael S. Depetris, Antonia M. Thomas, Per Johan Klasse, John P. Moore

Journal:

Year:

2011

Language:

english

File:

PDF, 1008 KB

english, 2011

14

Spondylodiscitis in the elderly patient: clinical mid-term results and quality of life

Rolf Sobottke, Marc Röllinghoff, Keta Zarghooni, Kourosh Zarghooni, Klaus Schlüter-Brust, Karl-Stefan Delank, Harald Seifert, Thomas Zweig, Peer Eysel

Journal:

Archives of Orthopaedic and Trauma Surgery

Year:

2010

Language:

english

File:

PDF, 461 KB

english, 2010

15

Neutralizing antibody and anti-retroviral drug sensitivities of HIV-1 isolates resistant to small molecule CCR5 inhibitors

Pavel Pugach, Thomas J. Ketas, Elizabeth Michael, John P. Moore

Journal:

Year:

2008

Language:

english

File:

PDF, 555 KB

english, 2008

16

Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques

Klasse, P. J., Ketas, Thomas J., Cottrell, Christopher A., Ozorowski, Gabriel, Debnath, Gargi, Camara, Diawoye, Francomano, Erik, Pugach, Pavel, Ringe, Rajesh P., LaBranche, Celia C., van Gils, Marit

Journal:

Year:

2018

Language:

english

File:

PDF, 11.99 MB

english, 2018

17

Enzymatic removal of mannose moieties can increase the immune response to HIV-1 gp120 in vivo

Kaustuv Banerjee, Sofija Andjelic, Per Johan Klasse, Yun Kang, Rogier W. Sanders, Elizabeth Michael, Robert J. Durso, Thomas J. Ketas, William C. Olson, John P. Moore

Journal:

Year:

2009

Language:

english

File:

PDF, 790 KB

english, 2009

18

HIV-1 clones resistant to a small molecule CCR5 inhibitor use the inhibitor-bound form of CCR5 for entry

Pavel Pugach, Andre J. Marozsan, Thomas J. Ketas, Elissa L. Landes, John P. Moore, Shawn E. Kuhmann

Journal:

Year:

2007

Language:

english

File:

PDF, 572 KB

english, 2007

19

Entry Inhibitors SCH-C, RANTES, and T-20 Block HIV Type 1 Replication in Multiple Cell Types

Ketas, Thomas J., Klasse, Per Johan, Spenlehauer, Catherine, Nesin, Mirjana, Frank, Ines, Pope, Melissa, Strizki, Julie M., Reyes, Gregory R., Baroudy, Bahige M., Moore, John P.

Journal:

AIDS Research and Human Retroviruses

Year:

2003

Language:

english

File:

PDF, 239 KB

english, 2003

20

Effects of adjuvants on HIV-1 envelope glycoprotein SOSIP trimers in vitro

Ozorowski, Gabriel, Cupo, Albert, Golabek, Michael, LoPiccolo, Michelle, Ketas, Thomas A., Cavallary, Matt, Cottrell, Christopher A., Klasse, PJ, Ward, Andrew B., Moore, John P.

Journal:

Journal of Virology

Year:

2018

Language:

english

File:

PDF, 2.86 MB

english, 2018

21

Closing and opening holes in the glycan shield of HIV-1 envelope glycoprotein SOSIP trimers can redirect the neutralizing antibody response to the newly unmasked epitopes

Ringe, Rajesh P., Pugach, Pavel, Cottrell, Christopher A., LaBranche, Celia C., Seabright, Gemma E., Ketas, Thomas J., Ozorowski, Gabriel, Kumar, Sonu, Schorcht, Anna, van Gils, Marit J., Crispin, Max

Journal:

Journal of Virology

Year:

2018

Language:

english

File:

PDF, 2.60 MB

english, 2018

22

Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens

Antanasijevic, Aleksandar, Ueda, George, Brouwer, Philip J. M., Copps, Jeffrey, Huang, Deli, Allen, Joel D., Cottrell, Christopher A., Yasmeen, Anila, Sewall, Leigh M., Bontjer, Ilja, Ketas, Thomas J.

Journal:

Year:

2020

File:

PDF, 4.31 MB

2020

23

Protection of macaques from vaginal SHIV challenge by vaginally delivered inhibitors of virus–cell fusion

Veazey, Ronald S., Klasse, Per Johan, Schader, Susan M., Hu, Qinxue, Ketas, Thomas J., Lu, Min, Marx, Preston A., Dufour, Jason, Colonno, Richard J., Shattock, Robin J.

Journal:

Year:

2005

Language:

english

File:

PDF, 185 KB

english, 2005

24

Effects of sequence changes in the HIV-1 gp41 fusion peptide on CCR5 inhibitor resistance

Cleo G. Anastassopoulou, Thomas J. Ketas, Rogier W. Sanders, Per Johan Klasse, John P. Moore

Journal:

Year:

2012

Language:

english

File:

PDF, 2.05 MB

english, 2012

25

The prolonged culture of human immunodeficiency virus type 1 in primary lymphocytes increases its sensitivity to neutralization by soluble CD4

Pavel Pugach, Shawn E Kuhmann, Joann Taylor, Andre J Marozsan, Amy Snyder, Thomas Ketas, Steven M Wolinsky, Bette T Korber, John P Moore

Journal:

Year:

2004

Language:

english

File:

PDF, 555 KB

english, 2004

26

Protection of Rhesus Macaques from Vaginal Infection by Vaginally Delivered Maraviroc, an Inhibitor of HIV‐1 Entry via the CCR5 Co‐Receptor

Veazey, Ronald S., Ketas, Thomas J., Dufour, Jason, Moroney‐Rasmussen, Terri, Green, Linda C., Klasse, P. J., Moore, John P.

Journal:

The Journal of Infectious Diseases

Year:

2010

Language:

english

File:

PDF, 450 KB

english, 2010

27

HIV-1 evades virus-specific IgG2 and IgA responses by targeting systemic and intestinal B cells via long-range intercellular conduits

Xu, Weifeng, Santini, Paul A, Sullivan, John S, He, Bing, Shan, Meimei, Ball, Susan C, Dyer, Wayne B, Ketas, Thomas J, Chadburn, Amy, Cohen-Gould, Leona

Journal:

Nature Immunology

Year:

2009

Language:

english

File:

PDF, 1.24 MB

english, 2009

28

A comparative immunogenicity study in rabbits of disulfide-stabilized, proteolytically cleaved, soluble trimeric human immunodeficiency virus type 1 gp140, trimeric cleavage-defective gp140 and monomeric gp120

Simon Beddows, Michael Franti, Antu K. Dey, Marc Kirschner, Sai Prasad N. Iyer, Danielle C. Fisch, Thomas Ketas, Eloisa Yuste, Ronald C. Desrosiers, Per Johan Klasse, Paul J. Maddon, William C. Olson,

Journal:

Year:

2007

Language:

english

File:

PDF, 443 KB

english, 2007

29

Single‐Dose Safety, Pharmacology, and Antiviral Activity of the Human Immunodeficiency Virus (HIV) Type 1 Entry Inhibitor PRO 542 in HIV‐Infected Adults

Jacobson, Jeffrey M., Lowy, Israel, Fletcher, Courtney V., O'Neill, Tobias J., Tran, Diep N. H., Ketas, Thomas J., Trkola, Alexandra, Klotman, Mary E., Maddon, Paul J., Olson, William C., Israel, Robe

Journal:

The Journal of Infectious Diseases

Year:

2000

Language:

english

File:

PDF, 84 KB

english, 2000

30

Inefficient entry of vicriviroc-resistant HIV-1 via the inhibitor-CCR5 complex at low cell surface CCR5 densities

Pavel Pugach, Neelanjana Ray, Per Johan Klasse, Thomas J. Ketas, Elizabeth Michael, Robert W. Doms, Benhur Lee, John P. Moore

Journal:

Year:

2009

Language:

english

File:

PDF, 489 KB

english, 2009

31

A Native-Like SOSIP.664 Trimer Based on an HIV-1 Subtype B env Gene

Pugach, Pavel, Ozorowski, Gabriel, Cupo, Albert, Ringe, Rajesh, Yasmeen, Anila, de Val, Natalia, Derking, Ronald, Kim, Helen J., Korzun, Jacob, Golabek, Michael, de los Reyes, Kevin, Ketas, Thomas J.,

Journal:

Journal of Virology

Year:

2015

Language:

english

File:

PDF, 1.74 MB

english, 2015

32

N-terminal substitutions in HIV-1 gp41 reduce the expression of non-trimeric envelope glycoproteins on the virus

Antu K. Dey, Kathryn B. David, Neelanjana Ray, Thomas J. Ketas, Per J. Klasse, Robert W. Doms, John P. Moore

Journal:

Year:

2008

Language:

english

File:

PDF, 674 KB

english, 2008

33

110 Nef-Trafficking Intercellular Highways for HIV Evasion of Antibody Production

Xu, Weifeng, Santini, Paul A, Sullivan, John S, He, Bing, Shan, Meimei, Ball, Susan C, Dyer, Wayne B, Ketas, Thomas J, Chadburn, Amy, Cohen-Gould, Leona, Knowles, Daniel M, Chiu, April, Sanders, Rogie

Journal:

JAIDS Journal of Acquired Immune Deficiency Syndromes

Year:

2011

Language:

english

File:

PDF, 2.24 MB

english, 2011

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